Posts tagged with 'clinical'
COVID-19 Is Prompting Innovation In Research TrialsRead the rest of this entry »
As scientists race to develop a vaccine and cure for the coronavirus that causes COVID-19, a remarkable collaboration has emerged among pharmaceutical and bioscience firms that in other times compete fiercely with each other.
Promoted by the Bill and Melinda Gates Foundation weeks before the virus was declared a pandemic, the initial 15 companies -- Novartis, Bristol-Myers Squibb, Eli Lilly and Gilead among them -- began sharing proprietary information about …
Clinical Research Hit By High TurnoverRead the rest of this entry »
Clinical research associates in the US are leaving jobs at the rate of 30% a year, says a new report from the consulting, tax and advisory firm, BDO.
Where turnover rates for these clinical monitoring professionals had been holding steady at 25%, the rate jumped between 2017 and 2018 by 4%. Outside the US, the global average is a modest 16%.
Turnover has plagued clinical / contract research organizations (CROs) …
How Big Is the Right Size For a Clinical Trial?Read the rest of this entry »
When a drug company embarks on a clinical trial, one of the risks it runs is the nonadherence of participants to the rules. In simplest terms, that means if a patient is to take a pill in the morning and another at night, deviating from the schedule is nonadherence. If too many participants deviate, the trial could fail.
An article in Applied Clinical Trials discusses the statistical implications of nonadherence. …
Survey: Clinical Trials Are Important, But Hard to FindRead the rest of this entry »
A global survey of attitudes and perceptions about clinical research trials found both the public and those who have participated in a trial convinced of their importance, but lacking in understanding about how they work and largely uninformed about opportunities for participation.
Conducted by the Center for Information and Study on Clinical Research Participation and published last week on JAMA Network Open, the purpose of the survey was to …
Millennials Are Putting Traditional Clinical Trial Model At RiskRead the rest of this entry »
Millennials have been accused of disrupting practically everything including credit cards and shopping malls. But until this spring, no one's accused them of putting the entire clinical trial model at risk.
But that's just what Kent Thoelke did. "Health care delivery and the technology adoption in health care delivery is already surpassing anything we do in drug development," he said, speaking at the inaugural event of the Bridging Clinical …
Online 'Listening' Is Improving Clinical Trial DesignRead the rest of this entry »
As companies strive to make their clinical trials more patient-centric, monitoring social media discussions is becoming an important tool to learn what matters to patients, their families and caregivers.
An article in Applied Clinical Trials says that by listening to what's being said in online forums trial designers and managers can gain insights they can incorporate to make their program more accommodating to their concerns. "Patient stories capture what it …
Clinical Trials Up 50x Since 2000Read the rest of this entry »
The number of clinical studies worldwide has exploded since the beginning of the century, increasing almost 50-fold to over 273,000 today. In the U.S. alone, there are currently 30,281 studies that are active, enrolling or recruiting, according to ClinicalTrials.gov.
The sheer number of these studies has contributed mightily to the challenge trial managers have in recruiting sufficient numbers of volunteers to participate. Three-quarters of clinical trial staff report missing …
Pharma Looks to Mobile Devices to Improve Clinical TrialsRead the rest of this entry »
Clinical trials are among the pharmaceutical industry's biggest headaches, and not just because the efficacy of a drug is at stake. Millions of dollars of R&D depend on successfully recruiting, managing and monitoring the trial volunteers, a process that itself is costly and time consuming.
That alone should be motivation for trial managers to leverage existing technology in order to improve patient convenience and reduce costs. Yet, as an article …
The Challenges of Clinical Trial RecruitingIn a world where clinical trials are becoming increasingly complex, one of the first challenges pharmaceutical companies, as well as other medical researchers, face is recruiting sufficient number of subjects to produce valid results.Read the rest of this entry »
How Apple Is Changing Clinical ResearchTwo weeks after Euan Ashley's cardiovascular study began last year, he already had collected data from 6,000 people.Read the rest of this entry »
“That's a remarkable number,” said Ashley, a geneticist who heads Stanford University's Center for Inherited Cardiovascular Disease.
Anyone with even a passing familiarity with clinical studies or trials will appreciate the understatement in Ashley's comment. Enrolling mere hundreds in even a simple research study is challenging enough. Finding, monitoring and managing …