Statins Show Promise in Reducing Death from Ovarian Cancer

Women with ovarian cancer who take statins to lower their cholesterol have a 40% lower death rate.

“These drugs are appealing as they are widely used, inexpensive, and well tolerated in most patients. The associated reduction in ovarian cancer mortality is promising,” said Dr. Kala Visvanathan, lead researcher of a new study presented last week during the American Association for Cancer Research Virtual Annual Meeting II.

Dr. Visvanathan, professor of epidemiology and oncology at Johns Hopkins Bloomberg School of Public Health and Sidney Kimmel Comprehensive Cancer Center in Baltimore, said all statins reduced the risk of dying, with lipophilic statins such as simvastatin and lovastatin, decreasing the likelihood by an average 43%. The most significant reductions occurred in those with high-grade serous carcinoma (40% reduction in mortality) and endometrioid ovarian cancer (50% reduction.)

The findings are the most comprehensive to date and add support to other, smaller studies showing similar improvements in ovarian cancer mortality from statins.

Most recently, a team of researchers at Australia’s QIMR Berghofer Medical Research Institute, analyzed 36 studies of several common medications taken by ovarian cancer patient. They concluded statin use showed the most promise. “Statin use is associated with better ovarian cancer survival,” they wrote in an article this month in Gynecologic Oncology, cautioning that, “Further study, preferably a clinical trial, is required.”

At the AACR meeting, Visvanathan said her team reviewed data on 10,062 ovarian cancer patients from the Finnish national cancer registry. 2,621 used statins, and 80% of those used lipophilic statins.

“Our results provide further evidence in support of the clinical evaluation of lipophilic statins as part of the treatment of ovarian cancer,” Visvanathan said.

Ovarian cancer is a rare cancer type, accounting for only about 1.2% of cancer cases diagnosed in the United States each year. Its five year survival rate is less than 50% because of the difficulty of diagnosing it until it has progressed to an advanced stage.

#WeAreGreenKey: Spotlight on Emily Gelman
General Interest Green Key News Professional Support Worklife

#WeAreGreenKey: Spotlight on Emily Gelman

Green Key Unlocked: Why It Pays to be a Paralegal
Accounting + Finance Financial Services General Interest Green Key News Legal Support Worklife

Green Key Unlocked: Why It Pays to be a Paralegal

Perks of a Hybrid Work Schedule
General Interest Green Key News Worklife

Perks of a Hybrid Work Schedule

Green Key Announces New Partners and Principals
Accounting + Finance Architecture + Engineering Financial Services General Interest Green Key News Healthcare Human Resources Information Technology Leadership + Management Pharma Professional Support Worklife

Green Key Announces New Partners and Principals

#WeAreGreenKey: Spotlight on Todd Bernard
Accounting + Finance General Interest Green Key News Human Resources Leadership + Management Worklife

#WeAreGreenKey: Spotlight on Todd Bernard

Employee Benefits for a Supportive Workplace
General Interest Green Key News Worklife

Employee Benefits for a Supportive Workplace

Forbes Names Green Key on America’s Best Temp Staffing Firms 2021
Green Key News

Forbes Names Green Key on America’s Best Temp Staffing Firms 2021

SIA Names Green Key Resources among Largest Staffing Firms in the US
Green Key News

SIA Names Green Key Resources among Largest Staffing Firms in the US

Wrapped Up: 2021 Corporate Trends
General Interest Green Key News Worklife

Wrapped Up: 2021 Corporate Trends

#WeAreGreenKey: Spotlight on Kelsey Kirk
General Interest Green Key News Professional Support Worklife

#WeAreGreenKey: Spotlight on Kelsey Kirk

Advantages of the “Stay Interview”
General Interest Green Key News Worklife

Advantages of the “Stay Interview”

Green Key Unlocked: What’s New in Architecture, Engineering, & Construction
Architecture + Engineering General Interest Green Key News Worklife

Green Key Unlocked: What’s New in Architecture, Engineering, & Construction

#WeAreGreenKey: Spotlight on Lisa Figuccio
Accounting + Finance General Interest Green Key News Worklife

#WeAreGreenKey: Spotlight on Lisa Figuccio

Tips for Writing Job Descriptions
General Interest Green Key News Worklife

Tips for Writing Job Descriptions

#WeAreGreenKey: Spotlight on Alexa Perrone
Accounting + Finance General Interest Green Key News Worklife

#WeAreGreenKey: Spotlight on Alexa Perrone

Tips for Employee Retention
General Interest

Tips for Employee Retention

#WeAreGreenKey: Spotlight on Brooke Stemen
General Interest Green Key News Worklife

#WeAreGreenKey: Spotlight on Brooke Stemen

Green Key Unlocked: The Value of the MBA
Accounting + Finance Financial Services General Interest Green Key News Marketing Technology Worklife

Green Key Unlocked: The Value of the MBA

#WeAreGreenKey: Spotlight on Amy Raymond
General Interest Green Key News Professional Support Worklife

#WeAreGreenKey: Spotlight on Amy Raymond

How to Tailor Your LinkedIn Profile for the Jobs You Want
General Interest Green Key News Worklife

How to Tailor Your LinkedIn Profile for the Jobs You Want

Latest Blog Posts
View All Posts
#WeAreGreenKey: Spotlight on Emily Gelman

#WeAreGreenKey: Spotlight on Emily Gelman

Today we catch up with Emily Gelman, Senior Recruiter on the Professional Support team at Green Key. Gelman joined the...
Read More
Green Key Unlocked: Why It Pays to be a Paralegal

Green Key Unlocked: Why It Pays to be a Paralegal

Paralegals are not only imperative to the industry, but recently in high demand. Due to law firms encouraging their entry...
Read More
Perks of a Hybrid Work Schedule

Perks of a Hybrid Work Schedule

The biggest perk of working hybrid is its flexibility. Allowing employees to choose when they come in grants them autonomy...
Read More